Description
Lucio Luzzatto and David R. Roper use real clinical cases to demonstrate diagnostic reasoning in haematology. Each case moves from the presenting history and initial blood tests to more focused investigations and a final explanation. Microscopy, biochemical testing, and molecular findings are considered together, showing how evidence from different sources fits a diagnosis.
Topics covered
- Sickle cell disease, thalassaemia, and haemoglobin variants.
- G6PD deficiency and other complex red-cell diagnostic problems.
- Stepwise interpretation of clinical, microscopic, biochemical, and molecular findings.
Who it’s for
Haematology trainees, biomedical scientists, medical students, and clinicians interested in laboratory diagnosis.
Study use: Pause after the initial case findings to build a differential, then compare your reasoning with the subsequent investigations.



